| Primary Identifier | MGI:3043590 | Allele Type | Targeted |
| Attribute String | Humanized sequence, Hypomorph | Gene | Ercc5 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Aspartic acid (811) was converted to alanine (D811A) and a loxP flanked PGK-neo cassette added via homologous recombination. This corresponds to a known human mutation and should abolish 3' excision activity. Northern blot analysis confirmed the presence of mRNA of normal size and amount. |