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Allele : Ercc5<tm4Shm> excision repair cross-complementing rodent repair deficiency, complementation group 5; targeted mutation 4, Tadahiro Shiomi

Primary Identifier  MGI:3043590 Allele Type  Targeted
Attribute String  Humanized sequence, Hypomorph Gene  Ercc5
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Aspartic acid (811) was converted to alanine (D811A) and a loxP flanked PGK-neo cassette added via homologous recombination. This corresponds to a known human mutation and should abolish 3' excision activity. Northern blot analysis confirmed the presence of mRNA of normal size and amount.
  • mutations:
  • Insertion
  • synonyms:
  • XpgD811A,
  • XpgD811A
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele