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Allele : Slamf1<tm1Cpt> signaling lymphocytic activation molecule family member 1; targeted mutation 1, Cox Terhorst

Primary Identifier  MGI:3044919 Allele Type  Targeted
Attribute String  Null/knockout Gene  Slamf1
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 2 and 3, IgV and IgC, which encode the complete ectodomain of the protein, were replaced with a neo cassette. Southern blot confirmed recombination in mutant mouse tail DNA and RT-PCR indicated no transcript in thymus or spleen of mutant mice. Flow cytometry demonstrated no surface expression in mutant thymocytes.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • SLAM<->,
  • SLAM<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

17 Publication categories