| Primary Identifier | MGI:3045877 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Nkx3-1 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | As a result of crossing Nkx3-1tm1Saa with transgenic mice expressing cre in the germ line, the floxed exon 2 and neo cassette were excised, leaving exon 1 and a single loxP site. RT-PCR analysis and immunohistochemical analyses confirmed loss of mRNA and protein expression in the posterior prostates of mutant mice. |
