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Allele : Pde3a<tm1Vman> phosphodiesterase 3A, cGMP inhibited; targeted mutation 1, Vincent Manganiello

Primary Identifier  MGI:3046786 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pde3a
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A neo cassette replaced exon 13, which encodes a portion of the catalytic domain. Western blot indicated mRNA of the mutant allele was transcribed and translated as shorter forms of the protein, putatively lacking the catalytic domain portion encoded by exon 13.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Pde3a<->,
  • Pde3a<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

14 Publication categories