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Allele : Myl2<tm1(Hand1)Tana> myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Makoto Tanaka
Primary Identifier  MGI:3047382 Allele Type  Targeted
Gene  Myl2 Transmission  Germline
Strain of Origin  129X1/SvJ Is Recombinase  false
Is Wild Type  false
molecularNote  Using a knock in strategy, FLAG-tagged Hand1 and a floxed neo were inserted into the Myl2 locus, replacing the coding sequence. Transient cre-mediated recombination excised the neo. Southern blot confirmed recombination and immunohistochemistry using an anti-FLAG antibody detected expression in cardio myocytes of mutant animals.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

4 Publication categories





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