Primary Identifier | MGI:3047791 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Xist |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 2.5 kb sequence was deleted between 5.5 and 8 kb upstream of Xist, including Rps12-ps1 and spanning a site thought to include an upstream promoter for Xist. A floxed PGK-neo was also inserted. RT-PCR showed presence of antisense transcription upstream of Xist in mutants where none is present in wild-type. |