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Allele : Tg(UAS-Shh)1Rth transgene insertion 1, David H Rowitch

Primary Identifier	MGI:3047220	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(UAS-Shh)1Rth
Strain of Origin	(C57BL/6J x CBA/J)F1	Is Recombinase	false
Is Wild Type	false

molecularNote

This transgene consists a yeast upstream activating sequence (UAS) driving expression of a full-length murine Shh cDNA. Expression of this transgene is dependent on GAL4 expression. Only one line in which Shh expression was promoted in response to GAL4 expression in the CNS was generated.

mutations:
Insertion

synonyms:
UAS-Shh,
UAS-Shh

earliestPublication:
Rowitch DH, et al. (1999) Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells. J Neurosci 19(20):8954-65

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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