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Allele : Dnmt3b<tm5.2Enl> DNA methyltransferase 3B; targeted mutation 5.2, En Li

Primary Identifier  MGI:3047834 Allele Type  Targeted
Attribute String  Null/knockout Gene  Dnmt3b
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  This allele was created by crossing Dnmt3btm5.1Enl with TNAP-cre mice, thereby excising the floxed segment, which includes exon 19, in the germline. This results in out-of-frame splicing of the mRNAs encoding all three active forms of the protein.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Dnmt3b<1lox>,
  • Dnmt3b<1lox>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories