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Allele : Otx2<tm7Sia> orthodenticle homeobox 2; targeted mutation 7, Shinichi Aizawa
Primary Identifier  MGI:3046841 Allele Type  Targeted
Attribute String  Modified regulatory region, Null/knockout Gene  Otx2
Transmission  Germline Strain of Origin  (C57BL/6NCrlj x CBA/JNCrlj)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The anterior neuroectoderm (AN) enhancer region (559 bp) was replaced with a floxed neomycin-resistance gene. Southern blot confirmed recombination and quantitative RT-PCR confirmed a reduction in gene expression in mutant embryos.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Otx2<deltaAN>,
  • Otx2<deltaAN1>,
  • Otx2<deltaAN1>,
  • Otx2<deltaAN>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories





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