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Allele : Pbx2<tm1Mlc> pre B cell leukemia homeobox 2; targeted mutation 1, Michael L Cleary

Primary Identifier  MGI:3047327 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pbx2
Transmission  Germline Strain of Origin  129S/Sv
Is Recombinase  false Is Wild Type  false
description  ES cell line = W9.5 (129S1/Sv-p+ Tyr+ Kitl+) or GS (129S6/SvEvTac).
molecularNote  A 248 bp portion of exon 3 and 68 bp of intron 3 were deleted and replaced with a PGK-neo cassette. Western blot of postnatal thymocytes and bone marrow cells indicated absence of protein. Western blot of fetal livers raised against a peptide mapping at the amino acid terminus detected neither full length nor truncated proteins. Northern blot also indicated no full length or truncated transcript.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Pbx2<->,
  • Pbx2<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

25 Publication categories