| Primary Identifier | MGI:3047327 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Pbx2 |
| Transmission | Germline | Strain of Origin | 129S/Sv |
| Is Recombinase | false | Is Wild Type | false |
| description | ES cell line = W9.5 (129S1/Sv-p+ Tyr+ Kitl+) or GS (129S6/SvEvTac). |
| molecularNote | A 248 bp portion of exon 3 and 68 bp of intron 3 were deleted and replaced with a PGK-neo cassette. Western blot of postnatal thymocytes and bone marrow cells indicated absence of protein. Western blot of fetal livers raised against a peptide mapping at the amino acid terminus detected neither full length nor truncated proteins. Northern blot also indicated no full length or truncated transcript. |