Primary Identifier | MGI:3047552 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Dnmt3a |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This allele was created by crossing Dnmt3atm3Enl with Ella-cre mice, thereby excising the floxed neo and leaving exon 19 floxed. Exon 19 encodes the conserved PC motif of the catalytic domain. |