Primary Identifier | MGI:3047571 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Cr2-cre)3Cgn |
Strain of Origin | Not Specified | Is Recombinase | true |
Is Wild Type | false |
molecularNote | This transgene consists of a cre expression cassette including a Kozak sequence, nuclear localization signal, and bovine growth hormone polyadenylation signal inserted into a BAC containing the Cr2 locus. The ATG in the first exon of Cr2 is also mutated in this allele. Cre mediated recombination is detected in 60% - 80% of mature B cells and is undetectable in pro/pre-B and immature B cells. |