Primary Identifier | MGI:3050794 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Gnas |
Transmission | Germline | Strain of Origin | 129S/SvEv |
Is Recombinase | false | Is Wild Type | false |
description | ES cell line = MAC3. |
molecularNote | 2.3 kb encompassing most of a differentially methylated region spanning 1A, 612 bp upstream of the promoter, was replaced with a floxed cassette containing Tkneo-pA, URA3 and tACE-Cre-pA. The cassette was deleted upon germ-line transmission, leaving a single loxP site. |