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Allele : Cd274<tm1Shr> CD274 antigen; targeted mutation 1, Arlene H Sharpe
Primary Identifier  MGI:3050803 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cd274
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  The signal and all of the IgV exon was replaced with a neomycin resistance gene. Southern blot confirmed recombination. Flow cytometry showed lack of expression in B cells, T cells, macrophages or DCs in mutants.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • PD-L1<->,
  • PD-L1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

0 Driven By

44 Publication categories





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