| Primary Identifier | MGI:3050815 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(HLA-A2/H2-K)1Scr |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgene expresses a human-mouse chimeric major histocompatibility class I protein composed of the leader sequence and the alpha1 and alpha2 domains of HLA-A2.1 joined to the alpha3, cytoplasmic and transmembrane domains of H2-Kb. Mice expressing this transgene exhibit HLA-A2.1-restricted CD8 T-cell responses to appropriate antigens. |
