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Allele : Unc13a<tm2Bros> unc-13 homolog A; targeted mutation 2, Nils Brose

Primary Identifier  MGI:3051217 Allele Type  Targeted
Attribute String  Hypomorph Gene  Unc13a
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A knock-in strategy was used to insert an H567K point mutation. Crossing mice with EIIa-cre mice resulted in the removal of a floxed neo downstream of the exon containing the mutation. Southern blot and PCR confirmed recombination. Western blot indicated protein levels similar to that of wild-type.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Munc13-1<H567K>,
  • Munc13-1<H567K>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories

Trail: Allele