Primary Identifier | MGI:3051217 | Allele Type | Targeted |
Attribute String | Hypomorph | Gene | Unc13a |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A knock-in strategy was used to insert an H567K point mutation. Crossing mice with EIIa-cre mice resulted in the removal of a floxed neo downstream of the exon containing the mutation. Southern blot and PCR confirmed recombination. Western blot indicated protein levels similar to that of wild-type. |