| Primary Identifier | MGI:3052324 | Allele Type | Transgenic |
| Attribute String | Reporter | Gene | Tg(CAG-lacZ-WGA)330Bbm |
| Strain of Origin | (C57BL/6J x CBA/J)F1 | Is Recombinase | false |
| Is Wild Type | false |
| description | Of three transgenic lines generated - called ZW5, ZW16 and ZW19 by Braz and colleagues (2002) - only ZW19, which exhibited the highest transmission rates, was propagated. |
| molecularNote | The transgene is comprised of a minimal immediate-early CMV enhancer/chicken beta-actin promoter driving ubiquitous expression of a lox-P flanked beta-galactosidase/neomycin phosphotransferase II (beta-geo) fusion gene that terminates in a strong, triple polyadenylation signal, followed by a C-terminally truncated wheat germ agglutinin coding sequence. Neuron-specific excision of the beta-geo gene by cre recombinase permits expression of the lectin, whose migration allows tracing of synapses involving the expressing cells. |
