| Primary Identifier | MGI:3052071 | Allele Type | Targeted |
| Attribute String | Inserted expressed sequence, Null/knockout | Gene | Ntrk1 |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting construct containing IRES, rat Ntrk3 cDNA, SV40 polyA, and a floxed PGK-neo was inserted after the first 40 bp of exon 2, deleting exons 3-6. Crossing with Actb-cre mice excised the floxed neo. Southern blot confirmed recombination. RT-PCR of dorsal root ganglia of heterozygotes shows expression of both Ntrk1 and the inserted Ntrk3. |
