Primary Identifier | MGI:3052072 | Allele Type | Targeted |
Attribute String | Modified isoform(s) | Gene | Crb1 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A hygromycin resistance cassette replaced 2.9 kb of the upstream promoter region, exon 1 and part of intron 1. Southern blot confirmed a smaller product size and immunoprecipitation indicated no detectable protein. However, LrCaptureSeq data indicates that deletion of this region disrupts isoforms A, A2, and C but leaves isoform B intact. |