Primary Identifier | MGI:3052540 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(APOA1)1Rub |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
description | Transgenic mice display a two fold increase in total plasma cholesterol levels and greater than a four fold decrease in the levels of mouse APOA1. Two lines were produced, A2 and A16. |
molecularNote | The transgene contains the human apolipoprotein A-I gene including the promoter. |