| Primary Identifier | MGI:3051523 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Psen1 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The alternatively spliced variant of human Psen-1-374 and a tk-neo cassette were inserted into exon 9. Southern blot and PCR confirmed the mutant allele. Psen-1 mRNA was not detected by Northern blot analysis of mutant mice. Western blot detected no full length or truncated protein. |
