Primary Identifier | MGI:3051543 | Allele Type | Targeted |
Attribute String | Inserted expressed sequence | Gene | Hprt1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A vector containing the P1 portion of the promoter from the rat Ggtp gene, mouse Agtr1a and the pA signal, as well as the human HPRT promoter, exon 1 and mouse Hprt exon 2 was inserted into ES cells with a deletion proximal to exon 3. Southern blot analysis confirmed recombination in ES cells. RT-PCR showed that the inserted sequence was expressed in transgenic kidneys. |