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Allele : Hprt1<tm1(Ggt1-Agtr1)Cof> hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Thomas M Coffman

Primary Identifier  MGI:3051543 Allele Type  Targeted
Attribute String  Inserted expressed sequence Gene  Hprt1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A vector containing the P1 portion of the promoter from the rat Ggtp gene, mouse Agtr1a and the pA signal, as well as the human HPRT promoter, exon 1 and mouse Hprt exon 2 was inserted into ES cells with a deletion proximal to exon 3. Southern blot analysis confirmed recombination in ES cells. RT-PCR showed that the inserted sequence was expressed in transgenic kidneys.
  • mutations:
  • Insertion
  • synonyms:
  • Gamma-GT-AT1A,
  • Gamma-GT-AT1A
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories