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Allele : Pik3cg<tm1Ehi> phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; targeted mutation 1, Emilio Hirsch

Primary Identifier  MGI:3051886 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Pik3cg
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 was replaced by a mutated form of human cDNA, in which the Lys833 was converted into Arg, followed by a neomycin resistance gene (Neor) cassette flanked by loxP sequences. Heterozygous mice were crossed with Balancer cre mice to delete the Neor cassette. RT-PCR revealed exclusive production of mutant mRNA.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • PI3Kgamma<KD>,
  • PI3Kgamma<KD>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

44 Publication categories