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Allele : Aadat<tm1Tag> aminoadipate aminotransferase; targeted mutation 1, Danilo A Tagle

Primary Identifier	MGI:3052711	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Aadat
Transmission	Germline	Strain of Origin	129S/SvEv
Is Recombinase	false	Is Wild Type	false

molecularNote

Exon 2 was replaced by a PGK-neo in reverse orientation, resulting in a frameshift downstream of the targeted region. Southern blot and PCR confirmed recombination. Northern blot showed no transcript in mutants and Western blot showed no protein was translated in mutant kidneys.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
mKat-2<->,
mKat-2<->

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

9 Publication categories

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