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Allele : Scn10a<tm2(cre)Jwo> sodium channel, voltage-gated, type X, alpha; targeted mutation 2, John N Wood

Primary Identifier  MGI:3053096 Allele Type  Targeted
Attribute String  Recombinase Gene  Scn10a
Transmission  Germline Strain of Origin  129
Is Recombinase  true Is Wild Type  false
molecularNote  Cre recombinase, 3' UTR of Scn10a, and an FRT flanked neo were knocked into the initiator methionine so that Cre replaced the ATG. Crossing with mice expressing Flp recombinase in the germ line excised the floxed neo. Cre expression was observed beginning at embryonic day 14 in small-diameter neurons in dorsal root, trigeminal, and nodose ganglia but absent in nonneuronal and CNS tissues.
  • mutations:
  • Insertion
  • synonyms:
  • Scn10a<tm2(cre)Jnw>,
  • nav1.8-cre,
  • NaV1.8<Cre>,
  • Nav1.8Cre,
  • Nav1.8Cre,
  • NaV1.8<Cre>,
  • Scn10a<tm2(cre)Jnw>,
  • nav1.8-cre
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

1 Driven By

130 Publication categories