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Allele : Tg(LckIl4)1315Dbl transgene insertion 1315, David Lewis

Primary Identifier	MGI:3052795	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(LckIl4)1315Dbl
Strain of Origin	(C57BL/6J x DBA/2J)F2	Is Recombinase	false
Is Wild Type	false

molecularNote

Transgenic mice overexpress the IL4 transgene under the control of the Lck promoter (lymphocyte protein tyrosine kinase). 8 copies of the transgene were estimated to have integrated into the genome. Expression of the transgene was detected in thymus tissue and by thymocytes.

mutations:
Insertion

earliestPublication:
Lewis DB, et al. (1991) Interleukin 4 expressed in situ selectively alters thymocyte development. J Exp Med 173(1):89-100

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

5 Publication categories

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