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Allele : Prnp<tm1Tuzi> prion protein; targeted mutation 1, Nadia L Tuzi

Primary Identifier  MGI:3052798 Allele Type  Targeted
Attribute String  Null/knockout Gene  Prnp
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed Betageo cassette was inserted into intron 2. PCR confirmed recombination in mice. Northern blot demonstrated that transcription was abolished and Western blot indicated a complete absence of protein in mutant brains.
  • mutations:
  • Insertion
  • synonyms:
  • Prp<stop>,
  • Prp<stop>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories