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Allele : Trex1<tm1Tld> three prime repair exonuclease 1; targeted mutation 1, Tomas Lindahl

Primary Identifier  MGI:3052754 Allele Type  Targeted
Attribute String  Null/knockout Gene  Trex1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance gene cassette replaced sequence encoding amino acids 103-207 of the encoded peptide, including conserved exonuclease magnesium binding motifs II and III. RT-PCR showed no transcript present in mutant spleens. Mutant livers did not demonstrate protein in Western blot analysis.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Trex1<->,
  • Trex1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

34 Publication categories