| Primary Identifier | MGI:3053826 | Allele Type | Transgenic |
| Attribute String | Inducible, Recombinase | Gene | Tg(Vil1-cre/ERT2)23Syr |
| Strain of Origin | (C57BL/6 x DBA/2) | Induced With | tamoxifen |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | A 9 kb segment of the regulatory region of the mouse Vil gene drives expression of cre recombinase fused to a mutated ligand-binding domain of the human estrogen receptor. Cre recombination is inducible with tamoxifen treatment in epithelial cells all along the crypt-villus axis and in undifferentiated progenitor cells in the crypt region. This is a representative record for the two lines generated (Fo23 and Fo24) that have the same inducible expression pattern. Only 1 copy of the transgene is integrated into these lines. |
