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Allele : Cd22<tm2Tft> CD22 antigen; targeted mutation 2, Thomas F Tedder

Primary Identifier  MGI:3054883 Allele Type  Targeted
Gene  Cd22 Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  R130 and R137 codons were targeted to generate codons encoding alanine residues. A floxed neomycin resistance gene was inserted between exons 4 and 5. Crossing with mice expressing Cre in the germ line excised the floxed neo. Immunoblot and flow cytometry confirmed protein was expressed in spleen cell lysates from mutant mice.
  • mutations:
  • Insertion
  • synonyms:
  • CD22AA,
  • CD22AA
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

5 Publication categories