| Primary Identifier | MGI:3054883 | Allele Type | Targeted |
| Gene | Cd22 | Transmission | Germline |
| Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | R130 and R137 codons were targeted to generate codons encoding alanine residues. A floxed neomycin resistance gene was inserted between exons 4 and 5. Crossing with mice expressing Cre in the germ line excised the floxed neo. Immunoblot and flow cytometry confirmed protein was expressed in spleen cell lysates from mutant mice. |