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Allele : Tg(CD2-Il2rb)H-1Ttg transgene insertion H-1, Tadatsugu Taniguchi

Primary Identifier  MGI:3054880 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(CD2-Il2rb)H-1Ttg
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  A cDNA encoding mouse interleukin 2 receptor beta lacking the carboxyl-terminal 131 amino acids - the H-region - of the extracellular domain of the mature protein was inserted into an expression vector containing 5 kb of 5' flanking sequence, including the promoter, transcription initiation site and first intron, and 5.5 kb of 3' flanking sequence including the locus control region (LCR) of the human CD2 gene. The CD2 promoter/enhancer direct expression in cells of the lymphoid lineage.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(Il2rb)H,
  • IL-2Rb H mutant,
  • IL-2Rbetac deltaH-mutant,
  • IL-2Rbetac deltaH-mutant,
  • Tg(CD2-Il2rb-deltaPro383-Tyr513)1Ttg,
  • IL-2Rb H mutant,
  • Tg(CD2-Il2rb-deltaPro383-Tyr513)1Ttg,
  • Tg(Il2rb)H
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

2 Publication categories