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Allele : Poli<d> polymerase (DNA directed), iota; polymerase iota deficient

Primary Identifier  MGI:3055735 Allele Type  Spontaneous
Attribute String  Null/knockout Gene  Poli
Inheritance Mode  Not Specified Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A C-to-A nonsense mutation changes codon 27 from serine (TCG) to an amber stop codon (TAG) (SW:Q6R3M4 p.S27*), and results in a truncated protein lacking any catalytic function. The allele was present in every 129 strain analyzed, including 129P3/J, 129X1/SvJ, 129P1/ReJ and 129P2/Ola. C57BL/6J and BALB/c mice did not contain the mutation.
  • mutations:
  • Single point mutation
  • synonyms:
  • Poli<129>,
  • Poli<->,
  • Poli<->,
  • Poli<129>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

6 Carried By

0 Driven By

13 Publication categories