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Allele : Nodal<tm5Rob> nodal growth differentiation factor; targeted mutation 5, Elizabeth J Robertson

Primary Identifier  MGI:3056345 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Nodal
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed hygromycin cassette was inserted in intron 1 and a third loxP site was placed in intron 3. In vitro cre recombination removed the floxed hygromycin cassette from properly targeted ES cell clones. Exons 2 and 3 were then left flanked by loxP sites. Mice were crossed to a protamine deleter strain to confirm that the recombined allele had a null phenotype.
  • mutations:
  • Insertion
  • synonyms:
  • Nodal<C>,
  • Nodal<C>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories