|  Help  |  About  |  Contact Us

Allele : Fosl1<tm2.1Wag> fos-like antigen 1; targeted mutation 2.1, Erwin F Wagner

Primary Identifier  MGI:3055993 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Fosl1
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  Crossing Fosl1tm2Wag with mice expressing Cre in the embryo proper created this allele in which the floxed region containing exons 3 and 4 (containing the dimerization and the DNA-binding domains) was excised. Upon excision, the 3' GFP was spliced to the N-terminal part of the transcript and was thereby activated. Western blot detected the fusion protein using an anti-GFP antibody. Immunofluorescence confirmed GFP activation.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • fra-1<->,
  • fra-1<->
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories