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Allele : Tg(DBHn-lacZ)8Rpk transgene insertion 8, Raj P Kapur

Primary Identifier  MGI:3055106 Allele Type  Transgenic
Attribute String  Reporter Gene  Tg(DBHn-lacZ)8Rpk
Strain of Origin  C57BL/6 x SJL Is Recombinase  false
Is Wild Type  false
description  This line was generated from founder 2860-8.

LacZ expression is seen in neurons of the locus ceruleus and other classic noradrenergic brain stem nuclei, sympathetic ganglion neurons, and adrenal chromaffin cells. LacZ expression is also observed in neurons of the enteric system, the retina, some sensory and all cranial parasympathetic ganglia, and some diencephalic and telencephalic brain nuclei.

molecularNote  A fragment of the human dopamine beta hydroxylase (DBH) gene, extending from a Sma1 site 5.8 kb upstream from the transcription start to an HpaII site 41 bp into the 5' untranslated region of exon 1, was fused to a bacterial beta-galactosidase reporter gene.
  • mutations:
  • Insertion
  • synonyms:
  • DBH-lacZ,
  • DBH-nlacZ(2860-8),
  • DBH-lacZ,
  • DBH-nlacZ(2860-8)
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

7 Publication categories