| Primary Identifier | MGI:3055292 | Allele Type | Spontaneous |
| Gene | Sobp | Inheritance Mode | Recessive |
| Strain of Origin | B6.129S2-Il6<tm1Kopf>/J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | This spontaneous mutation, discovered in a production colony at The Jackson Laboratory, was shown to be allelic with the original Jackson circler mutation by failure of the two alleles to complement one another. A G-to-T transversion occurs at coding nucleotide position 1894 (c.1894G>T) that converts the glycine codon at amino acid residue 632 to a stop codon (p.G632*). The resulting protein is reduced in length by 28%. |
