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Allele : Hmx3/Hmx2<tm3Tlu> H6 homeobox 2; targeted mutation 3, Thomas Lufkin

Primary Identifier  MGI:3055501 Allele Type  Targeted
Attribute String  Null/knockout Gene  Hmx2
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
description  ES cell line = R1 ((129X1/SvJ x 129S1/Sv)F1-Kitl+) or D3 (129S2/SvPas).
molecularNote  A targeting vector was designed to replace an 11kb genomic fragment encompassing the Hmx2 and Hmx3 homeoboxes with a neomycin resistance gene. The only potential protein to be translated would be a truncated Hmx3 protein lacking the C-terminal portion essential for DNA-binding.
  • mutations:
  • Intergenic deletion,
  • Insertion
  • synonyms:
  • Hmx2<->;Hmx3<->,
  • Hmx2<->;Hmx3<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories