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Allele : Sptbn4<tm1Msol> spectrin beta, non-erythrocytic 4; targeted mutation 1, Michele Solimena

Primary Identifier  MGI:3497744 Allele Type  Targeted
Attribute String  Null/knockout Gene  Sptbn4
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 of the epsilon 1 isoform, encoding the first methionine, was replaced by a neomycin resistance gene in opposite transcriptional orientation to the gene via homologous recombination. Western and immunofluorescence analysis confirmed the absence of protein in adult brain and sciatic nerve.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • betaIVepsilon1<->,
  • betaIVepsilon1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories