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Allele : Myb<tm1Epr> myeloblastosis oncogene; targeted mutation 1, E Premkumar Reddy

Primary Identifier  MGI:3497746 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Myb
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 6 encoding the high-affinity DNA-binding domain was flanked with loxP sites by homologous recombination of a construct that also contained a PGK-neo and thymidine kinase selection markers. The PGK-neo-thymidine kinase marker was excised by transient transfection of properly targeted ES cells with a cre-expressing plasmid and left exon 6 flanked by loxP sites.
  • mutations:
  • Insertion
  • synonyms:
  • myb<F>,
  • myb<F>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

10 Publication categories