| Primary Identifier | MGI:3487281 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Del(16Cbr1-Fam3b)1Rhr |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| description | A line of mice with segmental monosomy for Chr 16 was derived from descendants of the chimeric founder. |
| molecularNote | Deletion of a 3.9 Mb segment of Chr 16 was engineered by cre-mediated recombination between single loxP sites inserted into homologous chromosomes. This deleted segment contains mouse orthologs of 33 conserved and minimally conserved genes in the human Down syndrome critical region. |
