Primary Identifier | MGI:3497921 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ap3m2 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector was designed to replace downstream of the ATG for mu3B in exon 2 with an EGFP and a floxed neo. Cre expression excised the neo. RT-PCR indicated the absence of transcript in mutant brain and spinal cord. EGFP was detected in neurons throughout the brain. |