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Allele : Nbn<tm1.1Md> nibrin; targeted mutation 1.1, Martin Digweed

Primary Identifier  MGI:3505757 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nbn
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to flank exon 6 with loxP sites and to insert a floxed neo in intron 5. Cre expression excised the region containing the neo and exon 6. RT-PCR analysis indicated the presence of a shorter transcript consistent with the expected loss of sequence from the deleted exon.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Nbn<delta6>,
  • Nbn<delta6>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories