| Primary Identifier | MGI:3057263 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(CSF2)2Ygy |
| Strain of Origin | NIH Swiss | Is Recombinase | false |
| Is Wild Type | false |
| description | White blood cells from mice that carry this transgene in conjunction with Tg(IL3)1Ygy and Tg(KITLG)3Ygy and that are also homozygous for Prkdcscid are CD4-, CD8-, CD3-, IgM-, CD19- and Mac-1+ by flow cytometric (FMC) analysis. |
| molecularNote | The transgene construct contains the porcine colony stimulating factor 2 (granulocyte-macrophage) sequence (CSF2) controlled by the human cytomegalovirus promoter. The Tg(IL3)1Ygy, Tg(CSF2)2Ygy and Tg(KITLG)3Ygy transgenic constructs were co-injected into NIH/Swiss oocytes in David Bodine's lab at NCI. |
