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Allele : Tg(KITLG)3Ygy transgene insertion 3, Yong-guang Yang
Primary Identifier  MGI:3057265 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(KITLG)3Ygy
Strain of Origin  NIH Swiss Is Recombinase  false
Is Wild Type  false
description  White blood cells from mice that carry this transgene in conjunction with Tg(IL3)1Ygy and Tg(CSF2)2Ygy and that are also homozygous for Prkdcscid are CD4-, CD8-, CD3-, IgM-, CD19- and Mac-1+ by flow cytometric (FMC) analysis.
molecularNote  The transgene construct contains porcine kit ligand (KITL) controlled by the human cytomegalovirus promoter. The Tg(IL3)1Ygy, Tg(CSF2)2Ygy and Tg(KITLG)3Ygy transgenic constructs were co-injected into NIH/Swiss oocytes in David Bodine's lab at NCI.
  • mutations:
  • Insertion
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

6 Carried By

0 Driven By

8 Publication categories





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