| Primary Identifier | MGI:3487374 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Pkp2 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 7.8 kb genomic fragment within exon 1 and intron 1 was replaced by a neomycin selection cassette in opposite transcriptional orientation to the gene via homologous recombination, creating a stop codon after 43 aa. Western blot with an antibody against the COOH terminus and immunofluorescence analysis confirmed the absence of protein in E10.75 embryos and cardiac tissue, respectively. |
