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Transgene : Tg(APPSw)40Btla transgene insertion 40, Bruce Lamb
Primary Identifier  MGI:3510557 Organism  mouse, laboratory
Chromosome  13 Mgi Type  transgene
description  PHENOTYPE: Mice are viable and fertile. Mutant human APP transcripts and proteins are expressed similarly both spatially and temporally to the endogenous mouse product. Amyloid deposits occur in these animals. Mice are a model for familial Alzheimer's disease (FAD). [provided by MGI curators]
  • synonyms:
  • transgene insertion 40, Bruce Lamb,
  • R1.40,
  • APP<K670N/M671L>,
  • APP<K670/M671>,
  • Tg(APPSw)40Btla,
  • R1.40-YAC
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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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