| Primary Identifier | MGI:3510921 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Myl2-FGF19)1Dfre |
| Strain of Origin | FVB | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The human FGF19 cDNA was ligated to a rat myosin light chain 2 promoter and followed by the splice donor/acceptor sites present between exons 4 and 5 of the human growth hormaone gene. RT-PCR analysis of skeletal muscle biopsies showed the presence of human transcript in transgenic mice. Transgenic protein was verified by enzyme-linked immunosorbent assay. This record is a representative transgene as founder lines were not named. |
