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Allele : Snap25<tm2Mcw> synaptosomal-associated protein 25; targeted mutation 2, Michael C Wilson

Primary Identifier  MGI:3511662 Allele Type  Targeted
Gene  Snap25 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  A Tkneo selection gene flanked by loxP sites inserted in between the tandemly arranged exons 5a and 5b and exon 6 via homologous recombination, disrupting the developmental regulation of alternative splicing between exons 5a and 5b. In homozygous mutants, RT-PCR confirmed that expression of the two isoforms is altered such that the expression of the a isoform is increased and the b isoform is decreased.
  • mutations:
  • Insertion
  • synonyms:
  • Snap25<Tkneo>,
  • Snap25<Tkneo>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories