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Publication : Quantitative PCR genotyping assay for the Ts65Dn mouse model of Down syndrome.

First Author  Liu DP Year  2003
Journal  Biotechniques Volume  35
Issue  6 Pages  1170-4, 1176, 1178 passim
PubMed ID  14682051 Mgi Jnum  J:112549
Mgi Id  MGI:3662643 Doi  10.2144/03356st02
Citation  Liu DP, et al. (2003) Quantitative PCR genotyping assay for the Ts65Dn mouse model of Down syndrome. Biotechniques 35(6):1170-4, 1176, 1178 passim
abstractText  The Ts65Dn mouse is a segmentally trisomic model for Down syndrome. Until now, Ts65Dn mice have been identified by the laborious methods of either chromosomal analysis of cultured peripheral lymphocytes or fluorescent in situ hybridization (FISH). We report here a quantitative PCR method for genotyping Ts65Dn mice, as well as a phenotypic description for visually preclassifying mice to be genotyped.
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